Top 10 Famous People with Rare Diseases

“Famous individuals living with rare diseases not only inspire millions but also drive awareness and funding for conditions that are often misunderstood or overlooked.”
— Dr. Karen Leung, Clinical Geneticist

1. Michael J. Fox – Early-Onset Parkinson’s Disease

The Back to the Future star was diagnosed with Parkinson’s at age 29.

He’s now a leading advocate for Parkinson’s research and awareness.
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2. Venus Williams – Sjögren’s Syndrome

The tennis legend suffers from Sjögren’s syndrome, an autoimmune disorder causing dry eyes, dry mouth, and fatigue.

Despite the illness, she continues to compete professionally.
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3. Celine Dion – Stiff-Person Syndrome

A rare neurological disorder affecting only 1 in a million people.

It forced her to pause her singing career, but she remains resilient and hopeful.
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4. Morgan Freeman – Fibromyalgia

A condition causing widespread pain, fatigue, and tenderness.

Despite it, Freeman continues to act and narrate in major films and documentaries.
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5. Gaten Matarazzo – Cleidocranial Dysplasia (CCD)

A genetic condition affecting bone and dental development.

His character in Stranger Things also reflects his real-life condition, raising awareness worldwide.
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6. Harriet Tubman – Post-Traumatic Epilepsy

The historic abolitionist likely developed epilepsy after a childhood head injury.

She went on to become a fearless leader in the Underground Railroad movement.
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7. David Beckham – Obsessive-Compulsive Disorder (OCD)

While OCD is not rare, severe and disruptive forms like Beckham’s are.

He reportedly needs objects arranged in straight lines or in pairs to feel calm.
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8. Danny Glover – Dyslexia

The actor and activist struggled with reading difficulties as a child due to dyslexia.

He overcame it and built a highly successful career.
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9. Lady Gaga – Fibromyalgia

A condition causing chronic muscle pain, fatigue, and cognitive issues.

Gaga openly discussed it in her documentary to raise global awareness.
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10. Stephen Hawking – ALS (Amyotrophic Lateral Sclerosis)

One of the rarest and most severe motor neuron diseases.

Diagnosed at 21 and given only a few years to live, Hawking defied all odds and lived to 76, reshaping modern physics.
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